ASSOCIATION OF OZONIOTHERAPY WITH INTRACONAZOLE FOR THE TREATMENT OF FELINE SPOROTRICOSIS LESIONS: CASE REPORT.

Authors

DOI:

https://doi.org/10.35172/rvz.2023.v30.1493

Keywords:

Sporothrix sp., Zoonosis, Integrative therapies

Abstract

Sporotrichosis is a mycosis that is difficult to treat and has cats as one of the main hosts. Its clinical manifestations are characterized mainly by ulcerative continuity lesions in the skin and subcutaneous, lymphocutaneous, disseminated, with the presence of extracutaneous and fatal systemic signs. Its treatment is based on the administration of systemic and topical antifungals, but they cause significant damage to the organism and the environment. With few treatment options, ozone therapy can be indicated for the treatment of infectious conditions for sporotrichosis, due to its fungicidal, analgesic and anti-inflammatory action. The objective was to describe the clinical case of a feline, male, castrated 1 year and 8 months old, who had ulcerative lesions on the left pelvic limb and foot pad, diagnosed with sporotrichosis. Since there was no regression of the lesions with conventional treatment, ozone therapy was instituted using the bag inflation technique. After 12 sessions, the wounds were partially healed, the conventional treatment was maintained with the addition of the use of ozonated sunflower oil until the total regression of the lesions.

References

REFERÊNCIAS

- Guimarães TM, Guimarães AB. Esporotricose felina: Relatos de caso. PUBVET. 2021 Sep 6;16:191. https://doi.org/10.31533/pubvet.v16n01a1005.1-6 DOI: https://doi.org/10.31533/pubvet.v16n01a1005.1-6

- Moura AL. Uso da ozonioterapia como auxílio no tratamento das lesões de esporotricose felina: relato de caso. 2020 https://dspace.uniceplac.edu.br/handle/123456789/604

- Pinto PN. Avaliação da sensibilidade in vitro de Sporothrix brasiliensis frente à bases de Schiff para o desenvolvimento de novos fármacos para o tratamento da esporotricose felina. 2021 http://hdl.handle.net/1843/37934

- Santos ÁF. Esporotricose felina: distribuição das lesões e caracterização anatomopatológica em gatos utilizando diversos métodos de diagnóstico. 2019 http://hdl.handle.net/1843/35232

- Schubach TM, Schubach A. Sporotrichosis of cat and dog–review. Clin Vet. 2000;29:21-4.

- Gremião ID, Schubach TM, Pereira SA, Rodrigues AM, Honse CO, Barros MD. Treatment of refractory feline sporotrichosis with a combination of intralesional amphotericin B and oral itraconazole. Australian Veterinary Journal. 2011 Sep;89(9):346-51. https://doi.org/10.1111/j.1751-0813.2011.00804.x DOI: https://doi.org/10.1111/j.1751-0813.2011.00804.x

- Tavares W. Manual de antibióticos e quimioterápicos antiinfecciosos. InManual de Antibióticos e quimioterápicos Antiinfecciosos 1996 (pp. 792-792).

- Barros MB, Schubach TP, Coll JO, Gremião ID, Wanke B, Schubach A. Esporotricose: a evolução e os desafios de uma epidemia. Revista Panamericana de Salud Pública. 2010 Jun;27(6):455-60. https://doi.org/10.1590/0037-8682-0092-2013

- Pereira SA, Gremião ID, Kitada AA, Boechat JS, Viana PG, Schubach TM. The epidemiological scenario of feline sporotrichosis in Rio de Janeiro, State of Rio de Janeiro, Brazil. Revista da Sociedade Brasileira de Medicina Tropical. 2014;47:392-3. https://doi.org/10.1590/0037-8682-0092-2013 DOI: https://doi.org/10.1590/0037-8682-0092-2013

- Borges TL, Marangoni YG, Joaquim JG, Rossetto VJ, Nitta TY. Ozonioterapia no tratamento de cães com dermatite bacteriana: relato de dois casos. R. cient. eletr. Med. Vet.. 2019:11-p. https://pesquisa.bvsalud.org/portal/resource/pt/vti-21271

- Fuhr Marchesini B, Bazi Ribeiro S. Efeito da ozonioterapia na cicatrização de feridas. Fisioterapia Brasil. 2020 May 1;21(3). https://doi.org/10.33233/fb.v21i3.2931 DOI: https://doi.org/10.33233/fb.v21i3.2931

- Sanzo gl, Brito go, Lindemann p, França rt, Raquel a, Meinerz m. Alterações hematológicas encontradas em felinos com diagnóstico de esporotricose atendidos no hcv-ufpel. 2020.

- Silva, Jessica N. ,Sonia RL, Rodrigo C, Isabella DF, Tânia MP, Jeferson C, Anna BF, Sandro A. Diagnostic accuracy assessment of cytopathological examination of feline sporotrichosis. Medical mycology. 2015 Nov 1;53(8):880-4. https://10.1093/mmy/myv038 DOI: https://doi.org/10.1093/mmy/myv038

- Reis ÉG, Schubach TM, Pereira SA, Silva JN, Carvalho BW, Quintana MS, Gremião ID. Association of itraconazole and potassium iodide in the treatment of feline sporotrichosis: a prospective study. Medical mycology. 2016 Oct 1;54(7):684-90. https://doi.org/10.1093/mmy/myw027 DOI: https://doi.org/10.1093/mmy/myw027

- Cavalcanti EA, Ignácio TC, Kunrath SE, Meinerz AR, de Farias RO, da Gama Osório L. Esporotricose: Revisão. Pubvet. 2018 Sep 17;12:133. https://doi.org/10.31533/pubvet.v12n11a215.1-5 DOI: https://doi.org/10.31533/pubvet.v12n11a215.1-5

- Kim HS, Noh SU, Han YW, Kim KM, Kang H, Kim HO, Park YM. Therapeutic effects of topical application of ozone on acute cutaneous wound healing. Journal of Korean medical science. 2009 Jun 1;24(3):368-74. https://doi.org/10.3346/jkms.2009.24.3.368 DOI: https://doi.org/10.3346/jkms.2009.24.3.368

- Travagli V, Zanardi I, Valacchi G, Bocci V. Ozone and ozonated oils in skin diseases: a review. Mediators of inflammation. 2010 May;2010. https://doi.org/10.1155/2010/610418 DOI: https://doi.org/10.1155/2010/610418

- Nakamura AM. Efeito do óleo ozonizado na reparação de retalho cutâneo em ratos. 2020 http://hdl.handle.net/11449/193300

Published

2023-06-23

How to Cite

1.
Sampaio Calheiros A, de Moraes Calheiros LG, Moreira dos Santos Carnaúba RT, Medeiros Caldas Júnior N, Cecílio de Souza Filho N, Domingos Sales Lima Álvaro. ASSOCIATION OF OZONIOTHERAPY WITH INTRACONAZOLE FOR THE TREATMENT OF FELINE SPOROTRICOSIS LESIONS: CASE REPORT. RVZ [Internet]. 2023 Jun. 23 [cited 2024 May 20];30:1-6. Available from: https://rvz.emnuvens.com.br/rvz/article/view/1493