GLIAL CELLS ANEUPLOID FROM CULTURE OF EQUINE NEONATE SPINAL CORD

Abstract

The aim of this communication is to report the occurrence of glia cells aneuploid obtained from the culture of spinal cord of a newborn horse. Cells were maintained in culture until the sixth passage characterized by imunocytochemistry technique prior to cytogenetic analysis. Karyotype analysis showed loss or gain of one or more chromosomes in glial cells analyzed, when compared with the normal karyotype for equine specie. The occurrence of aneuploidy may be considered a normal finding in young neural cells, as well as a signal of several diseases. Thus, others cytogenetic studies should be performed to elucidate if the high occurrence of aneuploid glial cells in equine neonate nervous system is a physiological or pathological finding.