CANABIDIOL USO NA MEDICINA VETERINÁRIA - REVISÃO BIBLIOGRÁFICA
DOI:
https://doi.org/10.35172/rvz.2025.v32.1646Keywords:
Analgesia, Cannabis sativa, Marijuana, Δ9-tetrahydrocannabinol (Δ9-THC)Abstract
Cannabis, commonly known as marijuana, is a plant with many varieties. Sativa and Indica are the most well-known and used. The compounds extracted from this plant, especially cannabidiol (CBD) and tetrahydrocannabinol (THC), have been consistently used in research with therapeutic purposes for humans and animals. The compound in veterinary medicine is already used as an adjunct for chronic pain in rats, dogs, and horses, although with doses not yet elucidated. The medication brings comfort to animals, but especially in high doses, it can cause adverse effects. The present study aimed to compile the latest updates on the use of Cannabidiol in veterinary medicine through a literature review. It was observed that there was some difficulty in finding Brazilian articles on the subject, possibly due to the restrictions found in Brazilian legislation. From the results found, it was concluded that cannabis-based compounds are effective in the treatment of chronic conditions through analgesia, both in isolated use and when associated with other medications. Caution is necessary, especially with elderly patients who are prone to liver and kidney alterations.
References
SADDI, Luciana; ZEMEL, Maria de Lurdes de Souza. (Org). Maconha: os diversos aspectos, da história ao uso. São Paulo: Blucher, 2021.
BRIYNE, Nancy de et al. Cannabis, Cannabidiol Oils and Tetrahydrocannabinol—What Do Veterinarians Need to Know?. 2021. Luis Antunes.
SANTOS, Gabriel Vinícius dos. A utilização da Cannabis sativa para analgesia na Medicina Veterinária: Uma revisão sistemática; Centro Universitário do Planalto Central Apparecido dos Santos – UNICEPLAC; Curso de Medicina Veterinária; Trabalho de Conclusão de Curso; 2020.
MATOS, Rafaella L. A. et al. O uso do Canabidiol no tratamento da Epilepsia. Revista Virtual de Quimica. Rio de Janeiro, v. 9, n. 2, p. 01-29, 09 dez. 2016.
TRILICO, Matheus. Canabidiol: para que serve, o que é e como funciona o óleo de canabidiol na neurologia e na medicina. 2022.
ROBINSON, Rowan. O Grande Livro da Cannabis: guia completo de seu uso industrial, medicinal e ambiental. Rio de Janeiro: Siciliano, 1999. Maria Luiza x. de A. Borges.
HONÓRIO, Káthia Maria et al. Aspectos terapêuticos de compostos da planta Cannabis sativa. Química Nova, [S.L.], v. 29, n. 2, p. 318-325, abr. 2006. FapUNIFESP (SciELO). http://dx.doi.org/10.1590/s0100-40422006000200024. DOI: https://doi.org/10.1590/S0100-40422006000200024
UNIVERSITY, Pharmacology. Uso da cannabis em animais domésticos. CHNC, 2021. E-book.
SAÚDE, Redação Cannabis &. O que a ciência já sabe sobre o uso da Cannabis medicinal na Veterinária. 2020.
CFM. RESOLUÇÃO CFM 2113/2014: Aprova o uso compassivo do canabidiol para o tratamento de epilepsias da criança e do adolescente refratárias aos tratamentos convencionais. 2014.
FERNÁNDEZ-TRAPERO M, Pérez-Díaz C, Espejo-Porras F, de Lago E, Fernández-Ruiz J. Pharmacokinetics of Sativex® in Dogs: Towards a Potential Cannabinoid-Based Therapy for Canine Disorders. Biomolecules. 2020 Feb 11;10(2):279. http://10.3390/biom10020279 DOI: https://doi.org/10.3390/biom10020279
LANDA, L. et al. The use of cannabinoids in animals and therapeutic implications for veterinary medicine: a review. Veterinární Medicína, [S.L.], v. 61, n. 3, p. 111-122, 31 mar. 2016. Czech Academy of Agricultural Sciences. http://dx.doi.org/10.17221/8762-vetmed. DOI: https://doi.org/10.17221/8762-VETMED
CORSETTI, Sara et al. Cannabis sativa L. may reduce aggressive behaviour towards humans in shelter dogs. Scientific Reports. 2021. DOI: https://doi.org/10.1038/s41598-021-82439-2
WALLACE J-E, Kogan L-R, Carr E-C-J, Hellyer P-W. Motivations and expectations for using cannabis products to treat pain in humans and dogs: a mixed methods study. Journal of Cannabis Research 2020;2:36. https://doi.org/10.1186/s42238-020-00045-x DOI: https://doi.org/10.1186/s42238-020-00045-x
GAMBLE, Lauri-Jo et al. Pharmacokinetics, safety, and clinical efficacy of cannabidiol treatment in osteoarthritic dogs. Frontiers in veterinary science, v. 5, p. 165, 2018. DOI: https://doi.org/10.3389/fvets.2018.00165
MARTELLO, E. et al. Effects on pain mobility of a new diet supplement in dogs with osteoarthritis: A pilot Study. Annals of Clinical Laboratory Research, v. 7, n. 2, p. 304, 2019.
VUOLO, F., Soares, R. Z., Dall'Igna, D. M., Michels, M., Crippa, J. A., Hallak, J. E., Zuardi, A. W., Dal-Pizzol, F. Avaliação do papel do sistema canabidiol em um modelo de lesão renal por isquemia/reperfusão em animais; Revista Brasileira de Terapia Intensiva; vol.27 no.4 São Paulo Oct./Dec. 2015. DOI: https://doi.org/10.5935/0103-507X.20150064
KOGAN, Lori; HELLYER, Peter; DOWNING, Robin. (2020). The Use of CannabidiolRich Hemp Oil Extract to Treat Canine Osteoarthritis-Related Pain: A Pilot Study. AHVMA Journal, v. 28, p. 35-45, 2020.
ELLIS, K. L.; CONTINO, E. K. Treatment using cannabidiol in a horse with mechanical allodynia. Equine Veterinary Education, 2019. DOI: https://doi.org/10.1111/eve.13168
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Gabriel Marques Ungaretti, Michelle Ferraz, Ariane Moraes, Gabriel Pereira Tavares, Rochelle Gorczak
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Este obra está licenciado com uma Licença Creative Commons Atribuição-NãoComercial 4.0 Internacional.
