Undifferentiated carcinoma of the exocrine pancreas in dog
Case Report
DOI:
https://doi.org/10.35172/rvz.2017.v24.303Keywords:
neoplasia, immunohistochemistry, cytoqueratins, metastasisAbstract
The aim of this article is to describe a case of carcinoma of the exocrine pancreas in a 10 year
old, male, Poodle dog. The main complaint informed by the owner was dark urine and icterus.
The animal was presented with an unspecified symptomatology and physical exam
inconclusive. On abdominal ultrasound a nodule in the pancreas body was seen and confirmed
under exploratory laparotomy. Final diagnosis was confirmed by biopsy of the tissue and
immunohistochemistry evaluation. The tissue was negative for insulin, glucagon, somastatin
and vimentin; and positive for cytokeratin (AE1/AE3) and cytoqueratin 19. Final diagnosis
was carcinoma of the exocrine pancreas. The dog had a poor clinical response and died after
seven days post-surgery. On necropsy a remarkable structural change of pancreas and
regional metastatic disease were revealed; these findings were not seen on previously
exploratory surgery, describing the aggressiveness of this type of tumor.
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