HYPERLIPIDEMIA IN DOGS ATTENDED AT THE VETERINARY HOSPITAL SÃO JUDAS TADEU AND ITS CORRESPONDENCE WITH OBESITY: RETROSPECTIVE STUDY FROM 2018 TO 2020.

Authors

DOI:

https://doi.org/10.35172/rvz.2022.v29.663

Keywords:

Dog, Canine, Obesity, Hyperlipidemia, Hypertriglyceridemia, Hypercholesterolemia

Abstract

Currently, the anthropomorphized lifestyle of animals contributes to the intense development of obesity. Hyperlipidemia presents itself as one of the deleterious effects of excess weight on the health of dogs, although it has been little investigated. The term hyperlipidemia refers to an increase in the concentration of serum lipids (cholesterol, triglycerides or both). This study aimed to perform a retrospective and statistical analysis on animals that were considered obese by inspecting the body condition score, aiming to correlate obesity with the presence of hyperlipidemia. Seventy blood samples from patients treated at Veterinary Hospital São Judas from October 2018 to October 2020 who had already performed biochemical analyzes at the Hospital were reviewed and analyzed; the information destined to biochemical tests of triglycerides, cholesterol and weight was removed together with the assessment of body condition score (BCS) that was made in clinical consultation. It was found that 24 (34.2%) samples showed results above the reference values ​​for cholesterol and triglycerides. Among these 24 dogs, 21 (87.5%) had BCSequal to 7 or greater, representing overweight and/or obesity. None of the dogs had attended for care for the same reason and there were no complaints from the guardians regarding being overweight, so the changes found in biochemical tests were a clinical laboratory finding. Of the 21 dogs in the group that presented metabolic disorders, 12 dogs (57.2%) had both increased triglyceride and cholesterol levels, and then presenting a hyperlipidemia; 5 (23.8%) dogs had hypercholesterolemia and 4 (19%) had hypertrigliricedemia. These changes when compared to a control group of 19 animals without significant changes, revealed values ​​of statistical significance, suggesting a high frequency of hyperlipidemia in obese dogs, classified as moderately high with clinical importance, with prevalence in females.

References

– RIFAI N, BACHORIK PS, ALBERS JJ. Lipids, lipoproteins, and apolipoproteins. In: Tietz Textbook of Clinical Chemistry. Philadelphia, WB Saunders, 1999, p. 809–861.

– GINSBERG HN. Lipoprotein Physiology. Endocrinology and Metabolism Clinics of North America, New York. 1998 [cited 2021 Mai 10];09;27(3):503-519. Available from: https://doi.org/10.1016/S0889-8529(05)70023-2. DOI: https://doi.org/10.1016/S0889-8529(05)70023-2

– JERICÓ MM, KOGIKA MM, ANDRADE NETO JP. Tratado de Medicina Interna de cães e gatos. 4 ed. Rio de Janeiro: Roca, 2015.

– CAMARGO MA. Dislipidemias em animais. Seminário apresentado na disciplina de Fundamentos Bioquímicos dos Transtornos Metabólicos, Programa de Pós-Graduação em Ciências Veterinárias, Universidade Federal do Rio Grande do Sul. 2017; p 1-11. Disponível em: https://www.ufrgs.br/lacvet/site/wp-content/uploads/2018/01/dislipidemiasMonica.pdf. Acesso em: 10 mai. 2021.

– ELLIOT DA. Distúrbios do metabolismo. In: NELSON RW, COUTO CG. Medicina Interna de Pequenos Animais, 3 ed. Rio de Janeiro: Mosby Elsevier, 2006. p.782-787.

– CARVALHO GLC. Obesidade em cães e gatos: complicações metabólicas. Seminário apresentado na disciplina Transtornos Metabólico dos Animais Domésticos, Programa de Pós-Graduação em Ciências Veterinárias, Universidade Federal do Rio Grande do Sul, 2014; p 1-6. Disponível em: https://www.ufrgs.br/lacvet/site/wp-content/uploads/2014/11/obesidade.pdf. Acesso em: 25 mai. 2021. DOI: https://doi.org/10.22456/2317-8558.50228

– VEIGA APM. Obesidade e diabetes mellitus em pequenos animais. In: González, FHD, S AP. (eds.): Anais do II Simpósio de Patologia Clínica Veterinária da Região Sul do Brasil. Anais eletrônicos [...]; Porto Alegre (RS): Universidade Federal do Rio Grande do Sul. 2005. p.82-91. Disponível em: https://www.ufrgs.br/lacvet/site/wp-content/uploads/2013/05/II_simp_patol_clin2005.pdf. Acesso em: 04 de mai. 2021.

- VEIGA PM. Suscetibilidade a diabetes mellitus em cães obesos. Tese (Programa de Pós-Graduação em Ciências Veterinárias) - Universidade Federal do Rio Grande do Sul; 2007; Porto Alegre (RS). Disponível em: https://www.ufrgs.br/lacvet/site/wp-content/uploads/2013/05/tese_Angela.pdf. Acesso em: 15 abr. 2021.

– PORSANI MYH, TEIXEIRA FA, OLIVEIRA VV, PEDRINELLI V, AUGUSTO DIAS R, GERMAN AJ, BRUNETTO MA. Prevalence of canine obesity in the city of São Paulo, Brazil. Nature Research Scientific Reports. 2020; 10:14082, p 1-15. Available from: https://doi.org/10.1038/s41598-020-70937-8. Acesso em: 23 mai. 2021.

– HEYWARD V. ASEP methods recommendation: Body composition assessment. Journal of Exercise Physiology Online. 200; 4(4). p1-12 Available from: https://www.researchgate.net/publication/237305356_ASEP_methods_recommendation_Body_composition_assessment. Acesso em: 15 mai. 2021.

– DIEZ M, NGUYEN P. Obesity: epidemiology, pathophysiology and management of the obese dog. In: PIBOT P, BIOURGE V, ELLIOTT D. Encyclopedia of canine clinical nutrition. Airmargues: Diffo Print, 2006. p 2-57.

- FREEMAN L, BECVAROVA I, CAVE N, MACKAY C, NGUYEN P, BETTINA R,TAKASHIMA G, TIFFIN R, TSJIMOTO H, BEUKELEN P . Diretrizes Para a Avaliação Nutricional. 2020. p 1-16 . Disponível em: https://wsava.org/wp-content/uploads/2020/01/Global-Nutritional-Assesment-Guidelines-Portuguese.pdf. Acesso em: 23 mai. 2021.

- LAFLAMME DP. Development and validation of a body condition score system for dogs: a clinical tool. Canine Practice. 1997; v. 22; n. 3; p. 10-15. Available from: https://agris.fao.org/agris-search/search.do?recordID=US9742264. Acesso em: 18 abr. 2021.

– MAWBY DI. Comparison of various methods for estimating body fat in dogs. Journal of the American Animal Hospital Association. 2004; v 40; p 109–114. Available from: https://pubmed.ncbi.nlm.nih.gov/15007045/. Acesso em: 10 mai. 2021. DOI: https://doi.org/10.5326/0400109

– LAFLAMME DP. Understanding and managing obesity in dogs and cats. Vet Clin North Am Small Anim Pract. 2006; v. 36; p 1283-1295. Available from: https://doi.org/10.1016/j.cvsm.2006.08.005. Acesso em: 1 mai. 2021. DOI: https://doi.org/10.1016/j.cvsm.2006.08.005

– SILVA HC, BARION MRL, ALVARES AAA, SANTOS JMG. Distúrbios metabólicos em animais obesos. In: Mostra interna de trabalhos de iniciação científica, VI. 2012. Anais eletrônicos [...] Paraná: CESUMAR. Disponível em: http://www.cesumar.br/prppge/pesquisa/mostras/vi_mostra/heloisa_celis_silva.pdf. Acesso em: 22 abr. 2021.

– KANEKO J, HARVEY J, BRUSS M. Concepts of normality in clinical biochemistry. In: KANEKO J, HARVEY J, BRUSS M. Clinical biochemistry of domestic animals. 6 ed. San Diego: Academic, 2009. p 1-25.

– TILLEY LP, SMITH JR, F WK. The Five-Minute Veterinary Consult: Canine and Feline. 4 ed. Iowa: Blackwell Publishing Professional, 2007.

- JOHNSON MC. Hyperlipidemia disorders in dogs. Compendium on continuing education for the practicing veterinaria. May 2005; p. 361-370. Disponível em: http://assets.prod.vetlearn.com.s3.amazonaws.com/mmah/e4/e0b348cacb491dbe111fb713e5b677/filePV_27_05_361.pdf. Available from: 28 abr. 2021.

- XENOULIS PG, STEINER J M. Canine Hyperlipidaemia. Journal of Small Animal Practice; v 56, 2015; p. 595–605. Available from: https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.12396. Acesso em: 19 mai. 2021. DOI: https://doi.org/10.1111/jsap.12396

– WHITNEY MS. Evaluation of hyperlipidemias in dogs and cats. Seminars in Veterinary Medicine and Surgery, 1992; v 7; p. 292-300.

- FORD RB. Clinical management of lipemic patients. Compend Contin Educ Pract Vet.1996; v.18; p.1053-1065.

- USUI S, YASUDA H, KOKETSU Y. Lipoprotein cholesterol and triglyceride concentrations associated with dog body condition score: effect of recommended fasting duration on sample concentrations in Japanese private clinics. J. Vet. Med. Sci. Japan, 2015; 77(9): p 1063–1069. Available from: https://doi.org/10.1292/jvms.15-0032. Acesso em: 10 mai. 2021. DOI: https://doi.org/10.1292/jvms.15-0032

- NELSON RW. Parte sete: Distúrbios metabólicos e eletrolíticos. In: Medicina Interna de Pequenos Animais. 4 ed. Elsevier; 2010. p 860-866. Disponível em: https://doi.org/10.1038/s41598-020-70937-8. Acesso em: 21 mai. 2021. DOI: https://doi.org/10.1038/s41598-020-70937-8

- RODRIGUES, L F. Métodos de Avaliação da Condição Corporal em Cães. Trabalho de Conclusão de Curso (Programa de Pós-Graduação em Ciência Animal). Goiânia: Universidade Federal de Goiás; 2011. Disponível em: https://files.cercomp.ufg.br/weby/up/67/o/semi2011_Leticia_Furtado_2c.pdf. Acesso em: 28 abr. 2021.

– BRUNETTO MA, NOGUEIRA S, CÉSAR SÁ F, PEIXOTO M. VASCONCELLOS R S, FERRAUDO A J, CARCIOFI AC. Correspondência entre obesidade e hiperlipidemia em cães. Ciência Rural. fev 2011; v. 4; p 266-271. Disponível em: https://doi.org/10.1590/S0103-84782011005000004. Acesso em: 19 abr. 2021. DOI: https://doi.org/10.1590/S0103-84782011005000004

Published

2022-06-20

How to Cite

1.
de Oliveira Navarro T, Rodrigues Ambrósio S, Aparecida Feijó de Souza V, Rodrigues Soares M. HYPERLIPIDEMIA IN DOGS ATTENDED AT THE VETERINARY HOSPITAL SÃO JUDAS TADEU AND ITS CORRESPONDENCE WITH OBESITY: RETROSPECTIVE STUDY FROM 2018 TO 2020. RVZ [Internet]. 2022 Jun. 20 [cited 2024 Dec. 18];29:1-13. Available from: https://rvz.emnuvens.com.br/rvz/article/view/663

Issue

Section

Original Articles

Most read articles by the same author(s)