HEMATOLOGICAL AND BIOCHEMICAL REFERENCE VALUES IN DOMESTIC RABBITS (Oryctolagus cuniculus) FROM CANOAS CITY (RS)

Authors

DOI:

https://doi.org/10.35172/rvz.2021.v28.672

Keywords:

Blood count, clinical pathology, lagomorphs

Abstract

Domestic rabbits (Oryctolagus cuniculus) are bred for the production of meat, wool, fur, laboratory research and as companion animals. The objective of the present work is to determine the hematological and biochemical parameters of domestic rabbits of different breeds, at the Veterinary Hospital of Universidade Luterana do Brasil (ULBRA/CANOAS–RS). For biochemical determination, Labtest® reagent kits were used, analyzed in a BA–88 Mindray® spectrophotometer, the blood count was performed in a hematological counter (Sysmex® PocH–100iV Diff) with leukocyte differentiation by optical microscopy. Total plasma protein (TPP) was performed by refractometry, for fibrinogen the heat precipitation technique was used. The biochemical values ​​obtained were: Albumin 4.0 – 5.2 g/dL, alanine aminotransferase (ALT) 42.0 – 68.0 IU/L, creatinine 1.1 – 1.3 mg/dL, gamma-glutamyltransferase (GGT) 21.0 – 27.0 IU/L and urea ​​38.0 – 46.0 mg/dL. The hematological parameters were: RBC (x106μL) 5.4 – 6.8; packed cell volume (%) 41 – 49; mean cell volume (MCV) (fL) 71 – 77; red blood cell distribution width (RDW) (%) 13.2 – 17.8; platelets (μL) 328.000 – 544.000; TPP (g/dL) 6.4 – 7.7; fibrinogen (mg / dL) 12 – 300; leukocytes (μL) 5.800 – 10.800; heterophiles (μL) 1.400 – 4.400; eosinophils (μL) 0 – 360; lymphocytes (μL) 2.800 – 6.600; monocytes (μL) 40 – 800; basophils (μL) 0 – 36.

References

Andrade A, Pinto SC, Oliveira RS. Animais de laboratório: criação e experimentação. Rio de Janeiro: Editora Fiocruz; 2002.

Bush BM. Interpretação de resultados laboratoriais para clínicos de pequenos animais. São Paulo: Roca; 2004.

Campbell TW. Bioquímica clínica dos mamíferos: animais de laboratório e espécies variadas. In: Thrall MA, Weiser G, Allison RW, Campbell TW. Hematologia e bioquímica clínica veterinária. 2ed. Rio de Janeiro: Roca; 2015. Cap. 34, 1209–1232.

Melillo A. Topics in medicine and surgery: rabbit clinical pathology. Journal of Exotic Pet Medicine. 2007;16(3): 135–145. doi:10.1053/j.jepm.2007.06.002 DOI: https://doi.org/10.1053/j.jepm.2007.06.002

Moore DM, Zimmerman K, Smith SA. Hematological assessment in pet rabbits: blood sample collection and blood cell identification. Veterinary Clinics: Exotic Animal Practice. 2015;18(1): 9-19. doi:10.1016/j.cvex.2014.09.003. DOI: https://doi.org/10.1016/j.cvex.2014.09.003

Elamin KM. Age and sex effects on blood biochemical profile of local rabbits in Sudan. Wayamba Journal of Animal Science. 2013;5(1):548–553.

Kerr MG. Exames laboratoriais em medicina veterinária: bioquímica clínica e hematológica. 2ed. São Paulo: Roca; 2003.

Quinton JF. Novos animais de estimação. São Paulo: Roca; 2005.

Hernandes–Divers SJ. Coelhos. In: Carpenter JW. Formulário de animais exóticos. 3ed. São Paulo: Medvet; 2010. Cap. 10, 690–739.

Pessoa CA. Lagomorpha (Coelho, lebre e tapiti). In: Cubas ZS, Silva JCR, Catão-Dias JL. Tratado De Animais Selvagens. 2ed. São Paulo: Roca; 2014. Cap. 56, 1209–1237.

Özkan C, Kaya A, Akgül Y. Normal values of haematological and some biochemical parameters in serum and urine of New Zealand white rabbits. World Rabbit Science. 2012;20(4):253–259. doi: 10.4995/wrs.2012.1229. DOI: https://doi.org/10.4995/wrs.2012.1229

Emanuelli MP, Lopes STA, Maciel RM, Garmatz BC, Tavares MO. Concentração sérica de fosfatase alcalina, gama-glutamil transferase, ureia e creatinina em coelhos (Oryctolagus cuniculus). Cien.Anim.Bras. 2008;9(1):251–255.

Hoefer HL. Rabbit and ferret renal disease diagnosis. In: Fudge AM. Laboratory medicine: avian and exotic pets. Filadélfia: W.B Saunders Company, 2000. Cap. 38, 311–318.

Leineweber C, Muller E, Marschang RE. Blood reference intervals for rabbits (Oryctolagus cuniculus) from routine diagnostic sample. Tierarztl Prax Ausg K Kleintiere Heimtiere. 2018;46(6):393-398. doi: 10.1055/s-0038-1677403. DOI: https://doi.org/10.1055/s-0038-1677403

Gallego M. Laboratory reference intervals for systolic blood pressure, rectal temperature, hematology, biochemistry and venous blood gas and electrolytes in healthy pet rabbits. Open Veterinary Journal. 2017;7(1):203–207. doi: 10.4314/ovj.v7i3.1 DOI: https://doi.org/10.4314/ovj.v7i3.1

Murata H, Shimada N, Yoshioka M. Current research on acute phase proteins in veterinary diagnosis: an overview. The Veterinary Journal, 2004;167(1):28–40. doi: 10.1016/S1090-0233(03)00119-9. DOI: https://doi.org/10.1016/S1090-0233(03)00119-9

Valera RC, Milán JP. Utilidad del hemograma em la clínica equina. Equinus: medicina y cirugía equina. 2006;14(1):11–27.

Published

2021-12-22

How to Cite

1.
Brenner L, Laux J, de Oliveira Duarte K, Oliveira dos Santos E, da Costa Allgayer M. HEMATOLOGICAL AND BIOCHEMICAL REFERENCE VALUES IN DOMESTIC RABBITS (Oryctolagus cuniculus) FROM CANOAS CITY (RS). RVZ [Internet]. 2021 Dec. 22 [cited 2024 Nov. 24];28:1-7. Available from: https://rvz.emnuvens.com.br/rvz/article/view/672

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