RUMEN PROTECTED CHOLINE AND ITS EFFECT ON THE PREVENTION OF PREGNANCY TOXEMIA IN DAIRY EWES

Authors

  • Andressa Alaine Michailoff
  • Dom Diego Dall Agnol
  • Anderson Elias Bianchi
  • Fabiano Samuel Balistieri
  • Eliana Lucia Fiorentin
  • Ricardo Xavier Rocha
  • Jose Francisco Manta Bragança

Keywords:

sheep, ketosis, supplementation, energy metabolism.

Abstract

The aim of this study was to evaluate the supplementation of choline protected from ruminal
degradation in dairy sheep and its role in the prevention of pregnancy toxemia. Twenty
Lacaune ewes were used and divided into two groups, control group (GC, n =10) received
only the diet pre-partum and treated group (GCP, n=10), which in addition to the pre-partumdiet received 25g of rumen protected choline from the 110th day of pregnancy until the last
week prior to the expected date of delivery. Blood samples for measurement the blood
ketones performed in 110th of gestation (day zero), 117th days of gestation (day seven), 124th
day of gestation (day 14), 131th days of gestation (day 21) and 138th day gestation (day 28)
and serum cholesterol level was assessed at 124th days of gestation (day 14), 131th days of
gestation (day 21) and 138 days of gestation (day 28). The occurrence of disease clinical
ketosis (Pregnancy Toxemia) was also monitored during the experiment in both groups. The
amounts of ketones in the blood were lower GCP from day14 of the experiment, while
cholesterol values were higher in the same group on day 28. For the occurrence of pregnancy
toxemia, no animal showed signs of this disease in the GCP, but in the control group, one
animal showed clinical and two animals presents sub clinical ketosis. Concludes that the
25g/day choline supplementation protected from ruminal degradation for dairy sheep from the
110th day of pregnancy until the last week prior to the expected date of delivery reduced the
effects of negative energy balance and the incidence of ketosis in the final third of gestation in
sheep. 

References

HERDT TH. Ruminant adaptation to negative energy balance: influences on the etiology of ketosis and fatty liver. Veterinary Clinics of North America: Food Animal Practice, 2000; 16: 215-229.

SCHLUMBOHM C, HARMEVER J. Hyperketonemia impairs glucose metabolism in pregnant ewes. Journal of Dairy Science, 2004; 87: 350-358.

MAVROGIANNI VS, BROZOS C. Reflections on the causes and diagnosis of peri-parturient losses of ewes. Small Ruminant Research, 2008; 76: 77-82.

BANI ISAIL Z, AL-MAJALI A, AMIREH F, AL-RAWASHDEH O. Metabolic profiles in goat does in late pregnancy with and without subclinical pregnancy toxemia. Veterinary Clinical Pathology, 2008; 37: 434-437.

ROOK JS. Pregnancy toxemia of ewes, does, and beef cows. Veterinary Clinics of North America: Food Animal Practice, 2000; 16 (2): 293-317.

VAN SAUN RJ. Pregnancy toxemia in a flock of sheep. Journal of the American Veterinary Medical Association, 2000; 217 (10): 1536-1539.

SARGISON ND, SCOTT PR, PENNY CD, PIRIE RS, KELLY JM. Plasma enzymes and metabolites as potential prognostic indices of ovine pregnancy toxaemia: A preliminary study. British Veterinary Journal, 1994; 150 (3): 271-277.

GRUMMER RR. Nutritional and management strategies for the prevention of fatty liver in dairy cattle. Veterinary Journal London, 1995; 10 (20): 176.

PIEPENBRINK MS, OVERTON TR. Liver metabolism and production of cows fed increasing amounts of rumen-protected choline during the periparturient period. Journal Dairy Science, 2003; 5 (86): 1722-1733.

RADOSTITS OM. Clinica veterinária: um tratado de doenças dos bovinos, ovinos, suínos, caprinos e eqüinos. 9. ed. Rio de Janeiro: Guanabara Koogan, 2002. 1737p.

ANDREWS AH, HOLLAND-HOWES VE, WILKINSON JID. Naturally occurring pregnancy toxaemia in the ewe and treatment with recombinant bovine somatotropin. Small Ruminan Research, 1986; 23: 191-197.

BROZOS C, MAVROGIANNI V, FTHENAKIS GC. Treatment and control of periparturient metabolic diseases: Pregnancy toxemia, hypocalcemia, hypomagnesemia. Veterinary Clinics of North America: Food Animal Practice, 2011; 27: 105–113.

ANDRIGUETTO JM, PERLY L, MINARDI I, GEMAEL A, FLEMMING JS, SOUZA GA, BONA FILHO A. Nutrição Animal: As bases e os fundamentos da nutrição animal – Os alimentos. – São Paulo: Nobel, 2002, 387p.

BERCHIELLI TT, CANESIN RC, ANDRADE P. Estratégias de suplementação para ruminantes em pastagens. Revista Brasileira de Zootecnia/Brazilian Journal of Animal Science, 2006; 35 (suplemento): 353-370.

COOKE, J. P. Angiogenesis and the role of the endothelial nicotinic acetylcholine receptor. Life Sciences, 2007; 80 (24-25): 2347-2351.

KANEKO J.J.; H, J.W.; Bruss, M.L. Clinical Biochemistry of DomesticAnimals. 6th ed. Academic Press, San Diego, 2008, 916p.

GONZÁLEZ, Félix H. Díaz; SILVA, Sérgio Ceroni da; CERÓN, José Joaquín; CAMPOS, Rómulo. Introdução à bioquímica clínica veterinária. 2. ed. Porto Alegre: UFRGS, 2006. 358 p.

RIEGEL R.E. Radicais Livres. In:______ Bioquímica. 3. ed. São Leopoldo: Unisinos, 2002, p.507-536.

GRUMMER RR. Etiology of Lipid-Related Metabolic Disorders in Periparturient Dairy Cows. Journal Dairy Science, 1993; 76 (12): 3882-3896.

Published

2022-01-24

How to Cite

1.
Michailoff AA, Agnol DDD, Bianchi AE, Balistieri FS, Fiorentin EL, Rocha RX, Bragança JFM. RUMEN PROTECTED CHOLINE AND ITS EFFECT ON THE PREVENTION OF PREGNANCY TOXEMIA IN DAIRY EWES. RVZ [Internet]. 2022 Jan. 24 [cited 2024 Dec. 22];24(1):144-50. Available from: https://rvz.emnuvens.com.br/rvz/article/view/710

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