MYOFIBROBLASTS: A REVIEW

Authors

  • Ana Paula Batista Masseno
  • Camila Dias Porto
  • Louisiane de Carvalho Nunes
  • Julio Lopes Sequeira
  • Marco Antônio Alvarenga

Keywords:

Myofibroblasts, healing, extracellular matrix

Abstract

The healing is a complex phenomenon which restores the morphological and functional integrity of any tissue or organ injured. The recovery is a perfect and orderly cascade of cellular and molecular events that interact to have the rebuilding of tissue. The fibroblasts are the main cells involved in wound healing and have the main function to maintain the integrity of the tissue, the synthesis of components of extracellular matrix. The myofibroblasts are important components for the repair of injured tissue and appear after the end of the initial inflammatory phenomena. Myofibroblasts expressing α-actin of smooth muscle (α-SMA) to promote not only contraction but also synthesize high levels of proteases degrading the extracellular matrix.

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Published

2023-01-09

How to Cite

1.
Masseno APB, Porto CD, Nunes L de C, Sequeira JL, Alvarenga MA. MYOFIBROBLASTS: A REVIEW. RVZ [Internet]. 2023 Jan. 9 [cited 2024 Jul. 22];17(2):177-90. Available from: https://rvz.emnuvens.com.br/rvz/article/view/1194

Issue

Vol. 17 No. 2 (2010)

Section

Review Articles

License

Licença Creative Commons
Este obra está licenciado com uma Licença Creative Commons Atribuição-NãoComercial 4.0 Internacional.

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