AGING CHANGES OF CANINE BRAIN – IMAGING ASPECTS
Keywords:
aging, brain, computed tomography, dog, magnetic resonance imagingAbstract
Studies related to the verification of the aging changes in the brain of dogs have become very
important due to the growing medical care of elderly dogs. The determination of the findings
in a normal aging brain enables the identification of abnormalities in this process. In normal
condition, there are volumetric reduction of several brain regions associated with widening of
cerebral sulci; mild to moderate dilatation of the lateral ventricles; reduction in the height of
the hippocampus and enlargement of the temporal horns. Decrease in the attenuation of white
and gray matter as well as changes in intensity can also be observed in the brain images by
computed tomography and magnetic resonance imaging, respectively, in elderly patients. In
the latter imaging modality, hyperintense areas on T2-weighted and hypointense areas on T1-
weighted images have already been described in the brain of humans and dogs, respectively.
In these patients, an increase in the frequency of these lesions occurs with advancing age.
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