Benign Prostatic Hyperplasia in Dog: Comparison Diagnosis Methods

Abstract

enign Prostatic Hyperplasia (BPH) is the most common illness of the canine prostate, however, the comparison of different diagnostic methods for BPH as digital rectal examination, cytology, histology and immunohistochemistry is not widely studied in this specie, unlikely human beings. The purpose of this study was to evaluate, in twenty old dogs, cytological and histological alterations using immunostaining in the prostate gland. All the glands showed the presence of cystic BPH, associated or not with glandular or stromal hyperplasia. The immunostaining with AE1/AE3 cytokeratine was relevant in alveoli with flat epithelium. V9 vimentine showed to be moderate in areas with a severe stromal hyperplasia. Rectal palpation and the prostatic washing product compose auxiliary diagnostic methods for prostatic diseases, being essential the use of histopathology for a conclusive diagnosis. Prostatic tissue immunomarkers employment infers that the prostate with HPB demonstrate metabolic changes which react with immunostaining in hyperplasic cells.