OCCURRENCE OF NATURAL INFECTION FOR Leishmania spp. IN THE DOMICILED AND HUMAN CANINE POPULATION OF TRÊS LAGOAS-MS AND SPATIAL ANALYSIS

Authors

  • Maria Angelina da Silva Zuque Programa de Pós-Graduação em Doenças Tropicais – Faculdade de Medicina de Botucatu – FMB – Universidade Estadual Paulista – UNESP.
  • Suzane Manzini Agência Paulista de Tecnologia dos Agronegócios https://orcid.org/0000-0001-8052-5736
  • Thainá Valente Bertozzo Programa de Pós-Graduação em Doenças Tropicais – Faculdade de Medicina de Botucatu – FMB – Universidade Estadual Paulista – UNESP. https://orcid.org/0000-0002-7971-2021
  • Maria Fernanda Alves Martin Programa de Pós-Graduação em Doenças Tropicais – Faculdade de Medicina de Botucatu – FMB – Universidade Estadual Paulista – UNESP. https://orcid.org/0000-0001-9558-646X
  • Mirian dos Santos Paixão Programa de Pós-Graduação em Doenças Tropicais – Faculdade de Medicina de Botucatu – FMB – Universidade Estadual Paulista – UNESP.
  • Wesley José dos Santos Programa de Pós-Graduação em Doenças Tropicais – Faculdade de Medicina de Botucatu – FMB – Universidade Estadual Paulista – UNESP.
  • Lívia Maisa Guiraldi Programa de Pós-Graduação em Doenças Tropicais – Faculdade de Medicina de Botucatu – FMB – Universidade Estadual Paulista – UNESP.
  • Gabriela Pacheco Sanchez Programa de Pós-Graduação em Medicina Veterinária e Zootecnia – Faculdade de Medicina Veterinária e Zootecnia – FMVZ- Universidade Estadual Paulista – UNESP – Botucatu. https://orcid.org/0000-0002-0394-0589
  • Cilmery Suemi Kurokawa Programa de Pós-Graduação em Doenças Tropicais – Faculdade de Medicina de Botucatu – FMB – Universidade Estadual Paulista – UNESP. https://orcid.org/0000-0003-1380-7527
  • Isabella Neves Aires Faculdade de Ciências, Universidade Estadual Paulista – UNESP – Bauru. https://orcid.org/0000-0001-5285-3150
  • Nássarah Jabur Lot Rodrigues Programa de Pós-Graduação em Doenças Tropicais – Faculdade de Medicina de Botucatu – FMB – Universidade Estadual Paulista – UNESP. https://orcid.org/0000-0003-4970-2903
  • Simone Baldini Lucheis Agência Paulista de Tecnologia dos Agronegócios – APTA/SAA/Bauru https://orcid.org/0000-0002-4842-5281

DOI:

https://doi.org/10.35172/rvz.2022.v29.655

Keywords:

Visceral Leishmaniasis, natural infection, canines, diagnosis.

Abstract

Visceral Leishmaniasis (VL), a neglected disease of chronic and systemic character, caused by the parasite Leishmania spp. represents a public health problem, especially in countries with  vulnerable population, such as Brazil. Due to urbanization, dogs constitute an important reservoir in the disease’s urban cycle, preceding human cases, and contributing to the maintenance of Canine Visceral Leishmaniasis (CVL). However, few serological surveys added to the spatial analysis involving human and animal populations have been described in Três Lagoas. Therefore, the aim of this study was to identify and describe the occurrence of natural infection by Leishmania spp. in the human and domiciled canine population of Três Lagoas - MS, Brazil, using the serological techniques of Dual Path Platform (DPP), Enzyme Linked Immunosorbent Assay (ELISA) and Indirect Immunofluorescence Reaction (RIFI), as well as molecular techniques for Leishmania spp. and spatial analysis. For this study, 566 blood samples were collected from dogs. In addition, epidemiological information was collected from the municipal health system, and subsequently, spatial analysis was performed. As a result, 267 samples were reactive to the DPP test, 267 reactive to ELISA and 97 reactive to RIFI, with 95% of agreement between the DPP and ELISA methods. Sixteen samples submitted to PCR were positive for Leishmania spp. The use of georeferencing for canine CVL in Três Lagoas provided subsidies to identify areas that needed priority intervention for the control of Leishmaniasis. The presence of sandflies, associated with the geographic location, as well as the environmental conditions in the studied region, favored their dissemination, as well as the transmission of the disease to dogs and humans.

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Published

2022-02-09

How to Cite

1.
Zuque MA da S, Manzini S, Bertozzo TV, Martin MFA, Paixão M dos S, dos Santos WJ, Guiraldi LM, Sanchez GP, Kurokawa CS, Aires IN, Rodrigues NJL, Lucheis SB. OCCURRENCE OF NATURAL INFECTION FOR Leishmania spp. IN THE DOMICILED AND HUMAN CANINE POPULATION OF TRÊS LAGOAS-MS AND SPATIAL ANALYSIS. RVZ [Internet]. 2022 Feb. 9 [cited 2024 May 19];29:1-18. Available from: https://rvz.emnuvens.com.br/rvz/article/view/655

Issue

Vol. 29 (2022)

Section

Original Articles

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