AÇÃO DAS ESPÉCIES REATIVAS DE OXIGÊNIO NOS ESPERMATOZOIDES
Keywords:
free radicals, , oxidative stress, sperm cellsAbstract
So that spermatozoa can perform functions and achieve the goal that is fertilization, require
energy from adenosine triphosphate (ATP). During the energy metabolism is stored in the
form of high-energy electrons that are directed to the electron transport chain, comprised of
five supramolecular protein. In this process, there is the formation of a semiquinone anion
(Q¯) an intermediate radical that is eventually able to transfer this unpaired electron to O2 and
form reactive oxygen species,as the main superoxide, hydrogen peroxide and hydroxyl
radical. These molecules are highly reactive and sperm trigger processes that lead to
degradation and decrease in cell quality. However these same molecules that are often
considered great villains, also participate in mechanisms that culminate in fertilization and
zygote formation, thus acquiring great importance. With the advent of semen
cryopreservation and oxidative stress associated with the processing, reactive oxygen species
entered into evidence in the research, making it necessary to study its action and ways to
reduce oxidative stress.
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