DISFUNÇÕES RESPIRATÓRIAS FELINAS

CARACTERIZANDO E DIFERENCIANDO A ASMA E BRONQUITE FELINAS

Autores

DOI:

https://doi.org/10.35172/rvz.2024.v31.1571

Palavras-chave:

asma, bronquite, doença respiratória, obstrução, inflamação, gatos

Resumo

As doenças respiratórias são consideradas doenças graves e potencialmente deletérias. Dentre elas, a asma e a bronquite crônica caracterizam-se como disfunções respiratórias que ameaçam constantemente o bem-estar dos gatos. Os pacientes apresentam mudanças na estrutura respiratória, reversíveis ou não, devido ao extenso quadro inflamatório, que obstrui o fluxo de ar, permite o acúmulo de muco e reduz de lúmen das vias aéreas. Os gatos acometidos apresentam tosses, respiração ruidosa, dispneia, e, em muitos casos, assumem posição ortopneica. O diagnóstico pode ser obtido através de exames de rotina, uso de radiografias torácicas, coleta e análise de fluidos broncoalveolares, entre outros. O manejo terapêutico baseia-se, combinado ou não, no uso de drogas como broncodilatadores, corticoides, aerossóis e mudanças ambientais com objetivo de redução da exposição aos possíveis agentes alergênicos responsáveis pela incitação do quadro respiratório.

Biografia do Autor

Felipe Gaia de Sousa, Universidade Federal de Minas Gerais - UFMG

Universidade Federal de Minas Gerais - UFMG

Juliana Uchôa Ribeiro, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte/MG, Brasil

Universidade Federal de Minas Gerais - UFMG

Suzane Lilian Beier, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte/MG, Brasil

Universidade Federal de Minas Gerais - UFMG

Myrian Kátia Iser Teixeira, Clínica Veterinária Gato Leão Dourado, Belo Horizonte, Brasil

Clínica Veterinária Gato Leão Dourado, Belo Horizonte, Brasil

Referências

Bay JD, Johnson LR. Feline bronchial disease/asthma. In King LG.Textbook of respiratory disease in dogs and cats. Sant Louis: Saunders; 2004. p. 388-96. DOI: https://doi.org/10.1016/B978-0-7216-8706-3.50057-8

Kirschvink N, Leemans J, Delvaux F, Snaps F, Jaspart S, Evrard B, Delattre L, Cambier C, Clercx C, Gustin P. Inhaled fluticasone reduces bronchial responsiveness and airway inflammation in cats with mild chronic bronchitis. J Feline Med Surg. 2006;8(1):45-54. https://doi.org/10.1016/j.jfms.2005.07.001 DOI: https://doi.org/10.1016/j.jfms.2005.07.001

Cohn LA, DeClue AE, Cohen RL, Reinero CR. Effects of fluticasone propionate dosage in an experimental model of feline asthma. J Feline Med Surg. 2010;12(2):91-96. https://doi.org/10.1016/j.jfms.2009.05.024 DOI: https://doi.org/10.1016/j.jfms.2009.05.024

Padrid P. Feline asthma: diagnosis and treatment. Vet Clin North Am Small Ani Pract. 2000;30(6):1279-93. https://doi.org/10.1016/s0195-5616(00)06007-1 DOI: https://doi.org/10.1016/S0195-5616(00)06007-1

Junior AR, Cassiano FC. Doenças de traqueia e brônquios em gatos. In: Jericó MM, Andrade Neto JP, Kogika MM. Tratado de medicina interna de cães e gatos. 1ª ed. São Paulo: Roca; 2015. v. 2, p. 1280-1288.

Reinero CR, Lee-Fowler TM, Dodam JR, Cohn LA, Declue AE, Guntur VP. Endotracheal nebulization of N-acetylcysteine increases airway resistance in cats with experimental asthma. J Feline Med Surg. 2011;13(2):69-73. https://doi.org/10.1016/j.jfms.2010.09.010 DOI: https://doi.org/10.1016/j.jfms.2010.09.010

Padrid P. Asthma. In: August JR. Consultations in Feline Internal Medicine. 6th ed. Saint Louis: Saunders; 2010, p. 447-458.

Moses BL, Spaulding GL. Chronic bronchial disease of the cat. Vet Clin North Am Small Animal Pract. 1985;15(5):929-948. https://doi.org/10.1016/s0195-5616(85)50103-5 DOI: https://doi.org/10.1016/S0195-5616(85)50103-5

Corcoran B, Foster D, Luis Fuentes V. Feline asthma syndrome: a retrospective study of the clinical presentation in 29 cats. J Small Anim Pract. 1995;36(11):481-488, 1995. https://doi.org/10.1111/j.1748-5827.1995.tb02787.x DOI: https://doi.org/10.1111/j.1748-5827.1995.tb02787.x

Hirt AR. Felines Asthma bronchiale – Überblick und neue Erkenntnisse. Wien Tierarztl Monatsschr. 2003;90:110–123.

Venema C, Patterson C. Feline Asthma: What’s New and where might clinical practice be Heading? J Feline Med Surg. 2010;12(9):681-692. https://doi.org/10.1016/j.jfms.2010.07.012 DOI: https://doi.org/10.1016/j.jfms.2010.07.012

Kerins AM, Breathnach R. The respiratory system. In: Chandler EA, Gaskell RM, Gaskell CJ, editors. Feline medicine & therapeutics. 3rd ed. Oxford: Blackwell Publishing, 2004. p. 329-32.

Reche Junior A, Cassiano FC. Doenças de traqueia e brônquios em gatos. In: Jericó MM, Andrade Neto JP, Kogika MM. Tratado de Medicina Interna de Cães e Gatos. São Paulo: Roca, 2015. v.2. p. 1280-1288.

Grotheer M, Hirschberger J, Hartmann K, Castelletti N, Schulz B. Comparison of signalment, clinical, laboratory and radiographic parameters in cats with feline asthma and chronic bronchitis. J Feline Med Surg. 2020;22(7):649-655. https://doi.org/10.1177/1098612x19872428. DOI: https://doi.org/10.1177/1098612X19872428

Swift S, Dukes-Mcewan J, Fonfara S, Loureiro JF, Burrow R. Aetiology and outcome in 90 cats presenting with dyspnea in a referral population. J Small Anim Pract. 2009;50(9):466-73. https://doi.org/10.1111/j.1748-5827.2009.00767.x DOI: https://doi.org/10.1111/j.1748-5827.2009.00767.x

Guyton AC, Hall JE. Tratado de Fisiologia Médica. Rio de Janeiro: Elsevier Editora Ltda; 2011.

Nelson RE; Couto CG. Medicina interna de pequenos animais. Rio de Janeiro Elsevier; 2015.

Adamama-Moraitou KK, Patsikas MN, Koutinas AF. Feline lower airway disease: a retrospective study of 22 naturally occurring cases from Greece. J Feline Med Surg. 2004;6(4):227-33. https://doi.org/10.1016/j.jfms.2003.09.004 DOI: https://doi.org/10.1016/j.jfms.2003.09.004

Reinero CR, Declue AE, Rabinowitz P. Asthma in humans and cats: is there a common sensitivity to aeroallegens in shared environments? Environ Res. 2009;109(5):634–640. https://doi.org/10.1016/j.envres.2009.02.001 DOI: https://doi.org/10.1016/j.envres.2009.02.001

Reinero CR. Advances in the understanding of pathogenesis, and diagnostics and therapeutics for feline allergic asthma. Vet J. 2011;190(1):28-33. https://doi.org/10.1016/j.tvjl.2010.09.022 DOI: https://doi.org/10.1016/j.tvjl.2010.09.022

Baral RM. Doenças do trato respiratório inferior. In: Little SE, editor. O Gato: Medicina Interna. Rio de Janeiro: Roca; 2016. p. 829-842.

Trzil JE. Feline Asthma: Diagnostic and Treatment Update. Vet Clin Am Small Anim Pract. 2020;50(2):375–391. DOI: https://doi.org/10.1016/j.cvsm.2019.10.002

D'Annunzio G, Gobbo F, Avallone G, Bacci B, Sabattini S, Sarli G. Airway remodeling in feline lungs. Top Companion Anim Med.2022;46:100587. https://doi.org/10.1016/j.tcam.2021.100587 DOI: https://doi.org/10.1016/j.tcam.2021.100587

Vientós-Plotts AI, Ericsson AC, Rindt H, Grobman ME, Graham A, Bishop K, Cohn LA, Reinero CR. Dynamic changes of the respiratory microbiota and its relationship to fecal and blood microbiota in healthy young cats. PLoS ONE. 2017;12(3):e0173818. https://doi.org/10.1371/journal.pone.0173818 DOI: https://doi.org/10.1371/journal.pone.0173818

Norsworthy GD, editor. O paciente felino. São Paulo:Roca; 2009.

Trzil JE, Reinero CR. Update on feline asthma. Vet Clin North Am Small Anim Pract. 2014;44(1):91-105. https://doi.org/10.1016/j.cvsm.2013.08.006 DOI: https://doi.org/10.1016/j.cvsm.2013.08.006

Wexler-Mitchell E. Bronchial disease, chronic. 5 th ed. In: Norsworthy GD. The feline patient. New Jersey: Wiley, 2018, cap 27.

Taniguchi Y, Kobayashi M. Exposure to dogs and cats and risk of asthma: A retrospective study. Plos One. 2023;18(3):e0282184. https://doi.org/10.1371/journal.pone.0282184 DOI: https://doi.org/10.1371/journal.pone.0282184

Dye JA, Mckiernan BC, Rozanski EA, Hoffmann WE, Losonsky JM, Homco LD, Weisiger RM, Kakoma I. Bronchopulmonary disease in the cat: historical, physical, radiographic, clinicopathologic, and pulmonary functional evaluation of 24 affected and 15 healthy cats. J Vet Internal Med. 1996;10(6):385-400. https://doi.org/10.1111/j.1939-1676.1996.tb02086.x DOI: https://doi.org/10.1111/j.1939-1676.1996.tb02086.x

Foster SF, Allan GS, Martin P, Robertson ID, Malik R. Twenty-five cases of feline bronchial disease (1995–2000). J Feline Med Surg. 2004;6(3):181-188. https://doi.org/10.1016/j.jfms.2003.12.008 DOI: https://doi.org/10.1016/j.jfms.2003.12.008

Moise NS, Wiedenkeller D, Yeager AE, Blue JT, Scarlett J. Clinical, radiographic, and bronchial cytologic features of cats with bronchial disease: 65 cases (1980-1986). J Am Vet Med Assoc. 1989;194(10):1467-73.

Allerton FJW, Leemans J, Tual C, Bernaerts F, Kirschvink N, Clercx C. Correlation of bronchoalveolar eosinophilic percentage with airway responsiveness in cats with chronic bronchial disease. J Small Anim Pract. 2013;54:258–264. https://doi.org/10.1111/jsap.12070 DOI: https://doi.org/10.1111/jsap.12070

Morais HA. Doenças brônquicas em gatos: asma e bronquite crônica. In: Souza HJM, editor. Coletâneas em medicina e cirurgia felina. Rio de Janeiro: L.F.Livros de Veterinária LTDA: 2003, p. 147-153.

Henik RA, Yeager AE. Bronchopulmonary diseases. In: Sherding RG, editor. The Cat Diseases and Clinical Management. 1st ed. New York: Churchill Livingstone; 1994, p. 979–1052.

Klein BG, editor. Tratado de Fisiologia Veterinária. 5th ed. Rio de Janeiro: Elsevier Editora Ltda; 2014.

Charlson ES, Bittinger K, Chen J, Diamond JM, Li H, Collman RG, Bushman FD. Assessing Bacterial Populations in the Lung by Replicate Analysis of Samples from the Upper and Lower Respiratory Tracts. PLoS ONE. 2012;7(9):1-12. https://doi.org/10.1371/journal.pone.0042786 DOI: https://doi.org/10.1371/journal.pone.0042786

Hilty M, Burke C, Pedro H, Cardenas P, Bush A, Bossley C, Davies J, Ervine A, Poulter L, Pachter L, Moffatt MF, Cookson WOC. Disordered microbial communities in asthmatic airways. PLoS One. 2010;5(1):e8578. https://doi.org/10.1371/journal.pone.0008578 DOI: https://doi.org/10.1371/journal.pone.0008578

Huang, YJ, Nariya S, Harris JM, Lynch SV, Choy DF, Arron JR, Boushey H. The airway microbiome in patients with severe asthma: Associations with disease features and severity. Journal of Allergy Clinical Immunology. 2015;136(4):874-884. https://doi.org/10.1016/j.jaci.2015.05.044 DOI: https://doi.org/10.1016/j.jaci.2015.05.044

Dickson RP, Huffnagle GB. The Lung Microbiome: New Principles for Respiratory Bacteriology in Health and Disease. PLoS Pathogens. 2015;11(7):e1004923. https://doi.org/10.1371/journal.ppat.1004923 DOI: https://doi.org/10.1371/journal.ppat.1004923

Martin R, Miquel S, Langella P, Bermudez-Humaran LG. The role of metagenomics in understanding the human microbiome in health and disease. Virulence. 2014;5(3):413-423. https://doi.org/10.4161/viru.27864 DOI: https://doi.org/10.4161/viru.27864

Petersen C, Round JL. Defining dysbiosis and its influence on host immunity and disease. Cellular Microbiology. 2014;16(7):1024-1033. https://doi.org/10.1111/cmi.12308 DOI: https://doi.org/10.1111/cmi.12308

Werner M, Weeger J, Hörner-Schmid L, Weber K, Palić J, Shih J, Suchodolski JS, Pilla R, Schulz B. Comparison of the respiratory bacterial microbiome in cats with feline asthma and chronic bronchitis. Front Vet Sci. 2023;10:1148849. https://doi.org/10.3389/fvets.2023.1148849 DOI: https://doi.org/10.3389/fvets.2023.1148849

Vientós-Plotts AI, Ericsson AC, Reinero CR. The respiratory microbiota and its impact on health and disease in dogs and cats: A One Health perspective. J Vet Intern Med. 2023;37(5):1641-1655. https://doi.org/10.1111/jvim.16824 DOI: https://doi.org/10.1111/jvim.16824

Vientós-Plotts AI, Ericsson AC, McAdams ZL, Rindt H, Reinero CR. Respiratory dysbiosis in cats with spontaneous allergic asthma. Front Vet Sci. 2022;9:930385. https://doi.org/10.3389/fvets.2022.930385 DOI: https://doi.org/10.3389/fvets.2022.930385

Johnson LR, Vernau W. Bronchoscopic findings in 48 cats with spontaneous lower respiratory tract disease (2002–2009). J Vet Inter Med. 2011;25(2):236-243. https://doi.org/10.1111/j.1939-1676.2011.00688.x DOI: https://doi.org/10.1111/j.1939-1676.2011.00688.x

Byers CG, Nishi Dhupa B. Feline bronchial asthma: pathophysiology and diagnosis. Comp Cont Educ Pract Vet. 2005;27:418–425.

Rozanski E. Doença de vias respiratórias inferiores em felinos. In: Little SE, editor August Medicina Interna de Felinos. 7th ed. Rio de Janeiro: Elsevier; 2017, p. 447-451.

Tizard IR. Imunologia Veterinária. 9th ed. São Paulo:Guanabara Koogan; 2014.

Tizard IR. Imunologia Veterinária. 10th ed. São Paulo:Guanabara Koogan; 2017.

Garrity S, Lee-Fowler T, Reinero C. Feline asthma and heartworm disease: clinical features, diagnostics and therapeutics. J Feline Med Surg. 2019;21(9):825-834. https://doi.org/10.1177/1098612x18823348 DOI: https://doi.org/10.1177/1098612X18823348

Reinero CN, Decile K, Berghaus R, Willians K, Leutenegger C, Walby W, Schelegle ES, Hyde DM, Gershwin LJ. An experimental model of allergic asthma in cats sensitized to housedust mite or Bermud agrass allergen. Int Arch Allergy Immunol. 2004;135(2):117-31. https://doi.org/10.1159/000080654 DOI: https://doi.org/10.1159/000080654

Ettinger SJ. Diseases of trachea and upper airways. In: Ettinger SJ, Feldman EC. Textbook of Veterinary Internal Medicine. St. Louis: Saunders Elsevier; 2010. p. 1085-1086.

Decian A. Asma e bronquite Crônica em gatos domésticos [monografia de especialização. Porto Alegre (RS): Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul; 2019.

Johnson RL. Canine and Feline Respiratory Medicine. 2th ed. Hoboken: John Willey & Sons; 2020. Airway Diseases; p. 99-134.

Barchilon M, Reinero CR. Breathe easy: inhalational therapy for feline inflammatory airway disease. J Feline Med Surg. 2023;25(9):1098612X231193054. https://doi.org/10.1177/1098612x231193054 DOI: https://doi.org/10.1177/1098612X231193054

Padrid P. Asma. In: August JR. Medicina interna de felinos. Rio de Janeiro: Elsevier; 2011, v.1, p. 449-460.

Bordini CGG, Zanutto MS. Crise asmática. In: Calixto R. Emergências em medicina felina. Curitiba: Medvet; 2018, v.1, p. 48-56.

Gareis H, Hörner-Schmid L, Zablotski Y, Palić J, Schulz B. Evaluation of barometric whole-body plethysmography for therapy monitoring in cats with feline lower airway disease. Plos One. 2022;17(10):e0276927. https://doi.org/10.1371/journal.pone.0276927 DOI: https://doi.org/10.1371/journal.pone.0276927

Łobaczewski A, Czopowicz M, Moroz A, Mickiewicz M, Kosiec-Tworus A, Frymus T, Szaluś-Jordanow O. Integrated basic lung and heart ultrasound with X-ray (TUSX) for the diagnosis of asthma, chronic bronchitis and laryngeal paralysis, and treatment with inhaled fluticasone using home-made mask in dogs and cats. Pol J Vet Sci. 2022;25(2):335-344-335-344. https://doi.org/10.24425/pjvs.2022.141819 DOI: https://doi.org/10.24425/pjvs.2022.141819

Dear JD, Johnson LR. Lower respiratory tract endoscopy in the cat: diagnostic approach to bronchial disease. J Feline Med Surg. 2013;15(11):1019-1027. https://doi.org/10.1177/1098612x13508253 DOI: https://doi.org/10.1177/1098612X13508253

Schulz BS, Richter P, Weber K, Mueller RS, Wess G, Zenker I, Hartmann K. Detection of feline Mycoplasma species in cats with feline asthma and chronic bronchitis. J Feline Med Surg. 2014;16(12):943–949. https://doi.org/10.1177/1098612x14524969 DOI: https://doi.org/10.1177/1098612X14524969

Riabova K, Karsonova AV, van Hage M, Käck U, Konradsen JR, Grönlund H, Fomina D, Beltyukov E, Glazkova PA, Semenov DY, Valenta R, Karaulov A, Curin M Molecular Allergen-Specific IgE Recognition Profiles and Cumulative Specific IgE Levels Associated with Phenotypes of Cat Allergy. Int J Mol Sci. 2022;23(13):6984. https://doi.org/10.3390/ijms23136984 DOI: https://doi.org/10.3390/ijms23136984

Moriello KA, Stepien RL, Henik RA, Wenholz LJ. Pilot study: Prevalence of positive aeroallergen reactions in 10 cats with small-airway disease without concurrent skin disease. Vet Dermatol. 2007;18(2): 94–100. https://doi.org/10.1111/j.1365-3164.2007.00573.x DOI: https://doi.org/10.1111/j.1365-3164.2007.00573.x

Viana FAB. Guia Terapêutico Veterinário. 4th ed. Lagoa Santa: Gráfica e Editora CEM Ltda; 2019.

Suh S, Park MK. Glucocorticoid-Induced Diabetes Mellitus: An Important but Overlooked Problem. Endocrinol Metab. 2017;32(2):180-189, Mar. 2017. https://doi.org/10.3803/enm.2017.32.2.180 DOI: https://doi.org/10.3803/EnM.2017.32.2.180

Paulin MV, Caney SMA, Cosford KL. Online survey to determine client perceptions of feline chronic lower airway disease management: Response to therapy, side effects and challenges encountered. J Feline Med Surg. 2022; 24(12):1219-1227. https://doi.org/10.1177/1098612x211070988 DOI: https://doi.org/10.1177/1098612X211070988

Padrid PA, Cozzi P, Leff AR. Cyclosporine A inhibits airway reactivity and remodeling after chronic antigen challenge in cats. Am j Respir Crit Care Med. 1996;154(6):1812-1818. https://doi.org/10.1164/ajrccm.154.6.8970375 DOI: https://doi.org/10.1164/ajrccm.154.6.8970375

Plumb DC. Plumb´s Veterinary Drug Handbook. 5th ed. Ames: Blackwell Publishing; 2005.

Klenk FK, Desimoi V, Wolf G, Schulz BS. Evaluation of different cleaning methods for feline inhalation chambers after bacterial contamination. J Feline Med Surg. 2021;23(2):181-184. https://doi.org/10.1177/1098612x20913352 DOI: https://doi.org/10.1177/1098612X20913352

Downloads

Publicado

2024-03-26

Como Citar

1.
Gaia de Sousa F, Uchôa Ribeiro J, Lilian Beier S, Kátia Iser Teixeira M. DISFUNÇÕES RESPIRATÓRIAS FELINAS: CARACTERIZANDO E DIFERENCIANDO A ASMA E BRONQUITE FELINAS. RVZ [Internet]. 26º de março de 2024 [citado 13º de outubro de 2024];31:1-20. Disponível em: https://rvz.emnuvens.com.br/rvz/article/view/1571

Edição

Seção

Artigos de Revisão

Artigos mais lidos pelo mesmo(s) autor(es)