PRESUMPTIVE DIAGNOSIS OF SPINA BIFIDA IN CANINE PATIENT

Authors

  • Amanda Lorene Rabelo Presidente Antônio Carlos University : Conselheiro Lafaiete, Minas Gerais, BR
  • Felipe Gaia de Sousa Federal University of Minas Gerais - UFMG, Belo Horizonte/MG, Brazil. https://orcid.org/0000-0002-5078-7820
  • Suzane Lilian Beier Federal University of Minas Gerais - UFMG, Belo Horizonte/MG, Brazil. https://orcid.org/0000-0002-7352-5145

DOI:

https://doi.org/10.35172/rvz.2023.v30.1119

Keywords:

bone malformation, congenital alteration, locomotor alteration

Abstract

 The aim of this report is to describe a presumptive diagnosis of spina bifida in a mixed breed dog, due to previous diagnostic inconsistencies. Spina bifida is an uncommon congenital anomaly characterized by poor bone formation due to incomplete closure or the absence of the dorsal arch of the vertebral structure during the process of embryogenesis. Animals with this condition may have difficulties in the locomotion process, which constantly threatens the quality and survival of those affected. Spina bifida can present itself in four different forms and to varying degrees. A 5-month-old mixed breed dog was seen at a veterinary clinic in Conselheiro Lafaiete/MG with difficulties in the locomotion process and previous diagnostic inconsistencies in other veterinary services. On physical examination, he had kyphosis in the thoracic region and decreased proprioceptive capacity in the hind limbs. After radiographs were taken, morphological thoracic alterations were observed in the segment between the T5 to T9 vertebrae, with duplicated spinous processes and a decrease in the dimensions of the intervertebral space. The radiographic examination suggested presumptive evidence of thoracic spina bifida due to the unavailability of the tutor to perform more sensitive exams such as tomography and magnetic resonance. Therefore, drugs for pain and neuropathic control such as gabapentin and pregabalin were prescribed, at different times, until new recommendations, which have shown therapeutic efficacy to the patient. Currently, the patient uses a wheelchair adapted for locomotion due to the loss of movement of the hind limbs, in addition to weekly physical therapy follow-up and acupuncture sessions.

Author Biographies

Amanda Lorene Rabelo, Presidente Antônio Carlos University : Conselheiro Lafaiete, Minas Gerais, BR

Department of Veterinary Medicine, Presidente Antônio Carlos University : Conselheiro Lafaiete, Minas Gerais, Brasil

Felipe Gaia de Sousa, Federal University of Minas Gerais - UFMG, Belo Horizonte/MG, Brazil.

Department of Veterinary Clinic and Surgery, Veterinary School, Federal University of Minas Gerais – UFMG, Brazil.

Suzane Lilian Beier, Federal University of Minas Gerais - UFMG, Belo Horizonte/MG, Brazil.

Department of Veterinary Clinic and Surgery, Veterinary School, Federal University of Minas Gerais – UFMG, Brazil.

References

Ryan R, Gutierrez-Quintana R, Ter Haar G, De Decker S. Prevalence of thoracic vertebral malformations in French Bulldogs, Pugs and English Bulldogs with and without associated neurological deficits. Vet J. 2017;221:25-9. doi: 10.1016/j.tvjl.2017.01.018 DOI: https://doi.org/10.1016/j.tvjl.2017.01.018

Widmer WR, Thrall DE. Canine and Feline Vertebrae. In: Thrall DE, editor. Textbook of Veterinary Diagnostic Radiology. 7th ed. St. Louis, Missouri: Saunders; 2018. p. 248-69. DOI: https://doi.org/10.1016/B978-0-323-48247-9.00026-7

Miranda DFH, Ferraz MS, Azevedo-Junior JWC, Fortes EAM, Conde-Junior AM, Carvalho MAM. Spina bifida in newborn cat: case report. Semin Cienc Agrar. 2011; 32:1975-80. doi: 10.5433/1679-0359.2011V32N4SUP1P1975 DOI: https://doi.org/10.5433/1679-0359.2011v32Suplp1975

Thomas ZM, Podadera JM, Donahoe SL, Foo TSY, Weerakoon L, Mazrier H. Neural tube defects in four Shetland sheepdog puppies: clinical characterization and computed tomography investigation. Aust Vet J. 2020;98(7):312-18. doi: 10.1111/avj.12949 DOI: https://doi.org/10.1111/avj.12949

Lempek MC, Bordelo J, Veado JCC, Dias MIRD. Espinha bífida em um cão sem raça definida - Relato de caso. R Bras Med Vet. 2016;38(3):211-3.

Thrall DE, Robertson ID. Atlas of Normal Radiographic Anatomy and Anatomic Variants in the Dog and Cat. 2nd ed. St Louis: Saunders; 2016. 320 p.

Shamir M, Johnston D, Rochkind S. Surgical treatment of tethered spinal cord syndrome in a dog with myelomeningocele. Vet Rec. 2001;148(24):755-6. doi: 10.1136/vr.148.24.755. DOI: https://doi.org/10.1136/vr.148.24.755

Arias MVB, Marcasso RA, Margalho FN, Sierra S, Oliveira M, Oliveira RR. Spina bifida in three dogs. Braz J Vet Pathol. 2008;1(2): 64-9.

Moore KL, Persaud TVN. Embriologia Clínica. 2ed. Rio de Janeiro: Guanabara Koogan; 2013. 560 p.

Bertram S, ter Haar G, De Decker S. Congenital malformations of the lumbosacral vertebral column are common in neurologically normal French Bulldogs, English Bulldogs, and Pugs, with breed-specific differences. Vet Radiol Ultrasound. 2019;60(4):1-9. doi: 10.1111/vru.12753 DOI: https://doi.org/10.1111/vru.12753

Wilson JW, Kurtz HJ, Leipold HW, Lees GE. Spina Bifida in the Dog. Vet Pathol. 1979;16(2):165-79. doi: 10.1177/030098587901600202. DOI: https://doi.org/10.1177/030098587901600202

Taylor SM. Disorders of Spinal Cord. In: Nelson RW, Couto CG, editors. Small Animal Internal Medicine. 6th ed. St Louis, Missouri: Elsevier; 2020. p.1130-56.

Gomes CAR, Sampaio LM, Anacleto TP, Akamatsu A, Malagó R. Espinha bífida associada à síndrome do cão nadador: Relato de caso. Revista Científic@ Universitas. 2018;5(2):11-9.

Koslov N, Bhattarai B. Spina bifida occulta and surgical treatment in a Yorkshire terrier. J Small Anim Pract. 2019;60(10):636. doi: 10.1111/jsap.13053 DOI: https://doi.org/10.1111/jsap.13053

Bouma JL. Congenital Malformations of Vertebral Articular Processes in Dogs. Vet Clin Small Anim. 2016;46(2):307–326. doi: 10.1016/j.cvsm.2015.10.006 DOI: https://doi.org/10.1016/j.cvsm.2015.10.006

Romeu R, Gorczak R, Valandro MA. Analgesia farmacológica em pequenos animais. PUBVET. 2019;13(11):1-12. doi:10.31533/pubvet.v13n11a459.1-11 DOI: https://doi.org/10.31533/pubvet.v13n11a459.1-11

Kaminishi ÁPS, Hirano LQL. Uso de gabapentina no controle da dor em pequenos animais: revisão de literatura. Veterinária em Foco. 2017;14(2):29-35.

Plumb DC. Plumb’s Veterinary Drug Handbook. 7thed. Stockholm, Wisconsin: Wiley-Blackwell; 2011. 1567 p.

Sontag SC, Belletini ST, Tramontin RS, Conti JB, Pachaly EMV, Quessada AM, et al. Utilização de gabapentina para manejo clínico de dor neuropática em cães – Relato de caso. Arq Cienc Vet Zool UNIPAR. 2017;20(4):221-231. doi:10.25110/arqvet.v20i4.2017.6401 DOI: https://doi.org/10.25110/arqvet.v20i4.2017.6401

Viana FAB. Guia Terapêutico Veterinário. 4 ed. Lagoa Santa: Editora Cem; 2019. 528 p.

Toth C. Substitution of Gabapentin Therapy with Pregabalin Therapy in Neuropathic Pain due to Peripheral Neuropathy. Pain Med. 2010;11(3):456–65. doi: 10.1111/j.1526-4637.2009.00796.x DOI: https://doi.org/10.1111/j.1526-4637.2009.00796.x

Andrade SF. Manual de terapêutica veterinária: consulta rápida. 1ed. Rio de Janeiro: Roca; 2017. 569 p.

Salazar V, Dewey CW, Schwark W, Badgley BL, Gleed RD, Horne W, et al. Pharmacokinetics of single-dose oral pregabalin administration in normal dogs. Vet Anaesth Analg. 2009;36:574–80. doi:10.1111/j.1467-2995.2009.00486.x DOI: https://doi.org/10.1111/j.1467-2995.2009.00486.x

KuKanich B. Outpatient oral analgesics in dogs and cats beyond nonsteroidal antiinflammatory drugs: an evidence-based approach. Vet Clin North Am Small Anim Pract. 2013;43:1109–25. doi:10.1016/j.cvsm.2013.04.007 DOI: https://doi.org/10.1016/j.cvsm.2013.04.007

Sanchis-Mora S, Chang YM, Abeyesinghe SM, Fisher A, Upton N, Volk HA, Pelligand L. Pregabalin for the treatment of syringomyelia-associated neuropathic pain in dogs: A randomised, placebo-controlled, double-masked clinical trial. Vet J. 2019;250:55-62. doi: 10.1016/j.tvjl.2019.06.006. DOI: https://doi.org/10.1016/j.tvjl.2019.06.006

Published

2023-05-04

How to Cite

1.
Lorene Rabelo A, Gaia de Sousa F, Lilian Beier S. PRESUMPTIVE DIAGNOSIS OF SPINA BIFIDA IN CANINE PATIENT. RVZ [Internet]. 2023 May 4 [cited 2024 Jul. 3];30:1-10. Available from: https://rvz.emnuvens.com.br/rvz/article/view/1119

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